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"High purity coke would obviously contain fewer contaminants and cutting agents," says Nutt, of the extra side effects such cutting agents could potentially have – though adds that, really, they're not the primary concern: "Although harm from cutting agents has certainly been documented in cocaine and other drugs – see PMA in ecstasy pills, for example – cocaine dosing is the main issue here".
Other clinicians are reluctant to enrol patients in trials if the treatment concerned may result in extra side effects (White et al, 2008).
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Intra-thoracic and extra pulmonary side effects of these drugs include skin thickening, pleural effusions and thromboembolism.
The presence of an organic brain syndrome or previous brain injury [ 20], poorly-controlled antipsychotic-induced extra pyramidal side effects (EPSEs) and iron deficiency [ 26] have also found to increase the risk of NMS.
We also found that some participants were using stimulants to enable them to engage in activities, this may be a vicious circle as cocaine has been shown to increase extra-pyramidal side effects of antipsychotics [ 33] and some patients did cite extra-pyramidal side effects as a reason for drug use [ 16].
However, we noticed severe and intolerable extra-pyramidal side effects.
To treat extra-pyramidal side effects of neuroleptic medications due to risk of anticholinergic toxicity.
With long term use of >1 month due to high risk of confusion, hypotension, extra-pyramidal side effects, and falls.
This newly developed drug delivery system provides a unique method for selective targeting of GCs to inflamed joints which may potentially reduce adverse extra-articular side effects.
1 2 Prescription of antipsychotics requires caution given their association with a range of serious adverse effects including extra-pyramidal side effects with first-generation agents, weight gain and lipid/glucose dysregulation with second-generation agents.
Inflammatory joint diseases like rheumatoid arthritis (RA), as well as other rheumatic conditions such as ankylosing spondylitis and systemic lupus erythematosus, comprise a heterogeneous group of joint disorders that are all associated with extra-articular side effects, including bone involvement.
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