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Excessive imaging may also cause additional need for imaging because of false-positive and extra findings.
Additionally, addition of part of other body regions to limited whole body PET/CT scan may reveal extra findings.
Although the risk of thus missing a clinically relevant chromosomal abnormality is actually quite low (estimated range between 1 1600 and 1 4000), some commentators have suggested that the benefits of NIPT may not outweigh the loss of these extra findings at the stage of invasive follow-up.
This refers to extra findings from the ultrasound part of cFTS: cases of a greatly increased nuchal translucency (NT≥3.5 mm) are considered to require further testing for a range of possible abnormalities including congenital cardiovascular defects and genetic syndromes such as Noonan syndrome.
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In conclusion, in more than half of the patients undergoing MR-E additional extra-enteric findings were detected, the majority of extra-enteric MR-E findings being of low clinical importance, but approximately one third of the patients being diagnosed with findings of moderate or major clinical significance.
The state Court of Appeals rejected Mr. Blakely's arguments that only a jury could make the extra sentencing findings, and that the standard had to be beyond a reasonable doubt.
No studies have considered the costs and consequences of extra colonic findings from CTC. CTC was not cost-effective as a follow-up test for individuals with positive results from stool tests when compared with COL [24, 55].
Extra colonic findings from CTC will influence average screening costs and the subsequent health outcomes, and therefore should be considered in order to estimate the relevant costs and health outcomes of CTC strategies.
Extra luminal findings: phlegmon, abscess, fistula, free fluid.
Importantly, recruiting participants was challenging and required extra resources, findings consistent with prior reports [ 33, 68].
The specificity values of the CG54 tests to identify scarring, VUR or other abnormalities were all 1 compared to the RCP guideline results because they did not identify any extra positive findings.
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