Introducing NIPT as a triage test (cut-off 1 300) results in one extra case of T21 diagnosis missed after a false-negative NIPT result.
For every 1,000 people undergoing a cardiac CT scan, the radiation adds one extra case of cancer to the 420 that would normally occur.
The three models are hierarchical because the non-multiplicative nonlinearity model is a special case of the unrestricted nonlinearity model, which is itself a special case of the extra input nonlinearity model.
According to the National Academy of Sciences, for every 1,000 people exposed to this amount of radiation, one extra case of cancer is created by the testing.
The extra cost per extra case of T21 diagnosed versus NIPT as a triage test is about €840 000.
Therefore, the rise would translate to one extra case of bowel cancer in all those 100 lifetime bacon-eaters.
For children under 10 receiving head scans, about one extra case of leukaemia and one extra brain tumour per 10,000 patients would be expected after the procedure.
Based on the data in the study, a total of 498 people would need to take a statin before triggering one extra case of diabetes.
Last week, an analysis published in the Lancet found that for every 1,000 women using HRT for five years, there is one extra case of ovarian cancer – a slightly higher risk than seen in previous studies.
Rewards for the highest tally, displayed on "kill boards" included days off or an extra case of beer.
The researchers concluded that more than 9,000 women would need to take Yaz or Yasmin for one extra case of deep vein thrombosis to occur.
