This reduction was accompanied by rescue of Atgl /– macrophages from apoptotic cell death, as indicated by a decrease in externalization of phosphatidylserine, BAX protein expression and cytochrome c release and an increase in BCL2 protein expression.
In these cells, externalization of phosphatidylserine, cytochrome c release, increased expression of caspases-7, − 8 and − 9, reduced mitochondrial membrane potential and ROS overgeneration were also detected following LQFM064 (4) treatment.
In fact, enforced PS externalization induced by expression of active TMEM16F did not induce engulfment by macrophages in vitro or by dendritic cells (DCs) in vivo.
Externalization of PS is another key aspect of MP formation.
Upregulation of TNF-α leads to a rapid externalization of granules containing P-selectin (Weibel-Palade bodies), to an increased expression of E-selectin, and to a strong expression of the intercellular adhesion molecule 1 (ICAM-1) in endothelial cells.
The training module combined multiple skill sets for providing psychosocial support (for example, facilitating expression by talking, active listening, empathy, social support, externalization of interest, relaxation and recreation, and spirituality).
This review reports current knowledge on the impact of oxidative stress in RBC modifications with the surface appearance of senescent signals characterized by reduced expression of CD47 and glycophorin A and higher externalization of phosphatidylserine.
Externalization of phosphatidylserine and loss of membrane integrity was quantified after 48 h of αSyn expression using Annexin V/propidium iodide co-staining as previously described.
Regarding other RBC signaling pathways, the loss of glycophorin A [ 34], the externalization of phosphatidylserine (PS) [ 35], and the reduction of the "marker of self" integrin-associated protein CD47 expression [ 36] have been documented in circulating senescent RBCs.
It's an externalization of your progress".
Is the robot supposed to represent the sterile externalization of some deep and unspeakable lust?
