external trial

USAGE SUMMARY

The phrase "external trial" is correct and usable in written English.
It can be used in contexts related to testing, research, or experiments that occur outside of a controlled environment or organization. Example: "The researchers conducted an external trial to evaluate the effectiveness of the new drug in a real-world setting."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

5 human-written examples

The paper also reports on the experience gained in two external trial cases and results obtained by measuring the tractability of the implementation of the proposed validation approach.

Information Systems

We used the numbers of predicted key events to validate the model against external trial observations.

British Medical Journal

The framework does not oblige external trial investigators to provide post-trial benefits because it falls outside the scope of their typical role.

BMC Medical Ethics

The randomisation codes were generated by a staff member independent of the study team and held by the external trial monitor.

BMJ Open

Prior to randomisation, two independent liver histopathologists (SGH and RMB) from the central trial site (University Hospital Birmingham, UK) reviewed all of the liver biopsies (internal and external trial sites) of the potential participants to assess whether a diagnosis of 'definite' NASH was present.

BMJ Open

Human-verified similar examples from authoritative sources

Similar Expressions

55 human-written examples

An independent Data Safety and Monitoring Committee (DSMC) consisting of at least one Statistical Society of Australia Inc (SSAI -Accredited SSAI -Accreditede constatisticianiatric allergist and one external trials expert will monitor particonsultantety including unexpaediatricerse events which will be reported to the committee allergistccur.

BMJ Open

Nature also recommends that authors submit clinical trials data to external clinical trials databases (Nature Publishing Group 2012).

Environmental Health Perspectives

Our method of adjustment for use of nonstudy medicines —applying external randomized trial evidence for these drugs —uses a randomization-based efficacy estimate that is not subject to selection bias.

Plosone

Are external VHX trial stakeholders expected to work with research institutions and researchers in Myanmar to build their clinical research capacity and rely on the Myanmar health system to create post-trial access to study interventions?

BMC Medical Ethics

TOPCAT-P is a randomised two-arm parallel-group phase II external feasibility trial, comparing the effectiveness and cost-effectiveness of a personalised, nurse-led, psychoeducational intervention versus the augmented version of usual care beginning to be delivered in North Wales.

BMJ Open

By using epidemiological and cost data external to the trial, we were able to extrapolate from directly measured trial outcomes (DV disclosure and referral rates) to quality of life, health and economic outcomes.

BMJ Open

Expert writing Tips

Best practice

When discussing the generalizability of trial results, use "external trial" to highlight factors affecting the trial's applicability to broader, real-world settings. Consider explicitly stating what external factors are being considered.

Common error

Avoid using "external trial" when you actually mean to discuss factors affecting the internal validity of the study design, such as bias or confounding variables. "External trial" specifically refers to how well the results can be applied outside the original study context.

Linguistic Context

The phrase "external trial" primarily functions as a descriptor, modifying a noun to indicate a trial that involves external elements, such as oversight, data, or collaborators. As Ludwig AI explains, the phrase is considered correct and usable in written English.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

In summary, the phrase "external trial" is grammatically correct and usable, primarily appearing in scientific contexts to denote trials involving external elements impacting their validity or design. Ludwig AI confirms its correctness and provides relevant usage examples. When using the phrase, consider factors such as the scope of generalizability and the specific external elements being considered. Alternatives like "independent trial" or "third-party assessment of trial" may be appropriate depending on the intended nuance. The phrase's value lies in its capacity to delineate trials extending beyond controlled settings, thus influencing the interpretation and applicability of research outcomes.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

independent trial

Emphasizes impartiality and detachment from internal biases within the trial process.

third-party assessment of trial

Highlights the involvement of an unaffiliated entity evaluating the trial.

trial with external oversight

Focuses on the monitoring and supervision of the trial by an external body.

clinical study with external data

Indicates the inclusion of information from outside the immediate study for a more comprehensive analysis.

trial impacting external validity

Highlights the trial's influence on the generalizability of results to broader populations.

trial with external collaborators

Emphasizes cooperation with researchers or institutions outside the primary trial team.

field trial

Refers to a trial conducted in a real-world setting, outside of a controlled laboratory environment.

community-based trial

Highlights a trial conducted within a specific community, often involving local participants and resources.

multi-center trial

Describes a trial conducted at multiple locations, potentially involving different populations and settings.

pragmatic clinical trial

Focuses on the real-world effectiveness of an intervention, often conducted in routine clinical settings.

FAQs

What does "external validity" mean in the context of a clinical trial?

In clinical trials, "external validity" refers to how well the trial's results can be generalized to other populations, settings, and conditions. Factors "external to the trial", such as patient characteristics and treatment contexts, can significantly impact its external validity.

How can I improve the "external validity" of my clinical trial?

To improve the "external validity" of a clinical trial, consider including a diverse patient population that reflects the real-world population to whom the treatment will be applied. Also, ensure the trial setting and treatment protocols are representative of routine clinical practice.

What are some factors that can threaten the "external validity" of a research study?

Factors that can threaten the "external validity" of a research study include highly selective inclusion criteria, a non-representative study sample, artificial study settings, and differences between the trial interventions and real-world clinical practice.

How does an "external pilot trial" help in designing a larger clinical trial?

An "external pilot trial", also known as a rehearsal trial, helps assess the feasibility of a larger clinical trial. It can identify potential issues with recruitment, retention, and treatment adherence, allowing researchers to refine the study design and improve the likelihood of success.