The local flow patterns near the ostia, but external to the heart, were complex.
We know that the hyporeflective band external to the RPE/Bruch's membrane complex is in the vicinity of the choriocapillaris; however, the presence of this band on the scan is due to its optical properties, and this may not perfectly match the physical structure of the tissues or interfaces of interest.
By 72 h, the internal pO2 gradient showed a biphasic profile, where the minimum pO2 was external to the core of the bud complex.
Prigent-Combaret et al. (35) opined that the expression of genes in biofilms is evidently modulated by the dynamic physicochemical factors external to the cell and may involve complex regulatory pathways.
With the BrainWeb atlas we have been able not only to refine the external boundaries to the complex sulci (hills and valleys of the human brain cortex) to a voxel resolution of 1 mm, but also to allow the virtual glioma to grow and migrate within a true 3-dimensional representation of the human brain allowing each 1 mm thick slice of brain to interact with grey and white matter in adjacent planes.
Convergence of these internal and external signals to the mTOR complex, in turn, triggers various downstream outputs such as mRNA translation, protein synthesis, autophagy, cell proliferation, growth, and survival, which are critical for the lifespan of organisms (Kennedy and Kaeberlein, 2009; McCormick et al., 2011; Zoncu et al., 2011).
In general, Cox-2 is an inducible enzyme, but it has a basal level of expression in a subset of adult kidney tissues that is elevated in response to external stimuli, highlighting the complex regulation of this gene [ 3].
Novices are more likely to attribute external control to complex systems and to focus on stepwise solutions.
For Hawley, the explanatory variables are the makeup of the population, the external environment, the complex of organizations, and technology.
The flow condition of water supply pipelines are affected by terrain, buildings and other external factors, easy to produce the complex phenomenon of hydraulic transient.
Poor guideline uptake may be due to external factors such as the complex and competing demands on providers' time, organizational constraints, and lack of knowledge; as well as characteristics of the guidelines themselves (i.e., intrinsic factors).
