external signaling molecules

USAGE SUMMARY

The phrase "external signaling molecules" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in biology or biochemistry, to refer to molecules that transmit signals between cells or organisms. Example: "The study focused on the role of external signaling molecules in cell communication and their impact on cellular responses."

✓ Grammatically correct

Science

Human-verified similar examples from authoritative sources

Similar Expressions

60 human-written examples

Here, we imply that the receptors for the external signalling molecules are always available and functional in SFB.

BMC Systems Biology

Note, that TGFβ1 (TGFB1) and TNFα (TNF) are the only entities playing a dual role as both external signal molecules and target genes because of their introduction into the simulation as starting effectors.

BMC Systems Biology

Its development is already known to respond to a number of external signalling molecules, including Gdnf, Fgfs, Bmps, angiotensin and components of the basement membrane, and to a number of intracellular signalling paths including MAP-kinase, PI-3-kinase Wnt/PCP and Rock (for reviews, see Sakurai, 2003; Yosypiv, 2004; Michos, 2009).

Biology Open

In the resting state, SHIP2 resides in the cytosol and perinuclear area, but stimulation by external signal molecules effects recruitment to the plasma membrane where several other proteins may dock to motifs such as the SH2 domain, proline-rich sequences, and the SAM domain that may allow the enzyme to coordinate cell-specific activities.

ACS Chemical Biology

Examples of these mechanisms include the action of transcription factors (particularly those considered to be pioneer and bookmarking factors), noncoding RNAs, covalent modification of DNA and histone proteins (with chemical motifs such as methylation groups), and the action of the agents that create these modifications, as well as external signalling molecules.

Briefings in Functional Genomics

The evolution of receptors has accompanied the development of mechanisms that permit external chemical signaling molecules, the first messengers, to direct the activities of cells in a variety of ways with high specificity and precise control in terms of extent and duration.

Signal Transduction

In any case, the homogeneity found in the gene expression profiles of human melanocytes grown in BSE-containing media suggests that melanocytes from both light and dark pigmentation donors may have the same genetic ability to produce melanin if subject to the same level of external (paracrine) signaling molecules, at least above a certain concentration.

BMC Evolutionary Biology

A transcription factor is classified as "external" when the sensed signaling molecules is localized outside the cell, and "internal" when the sensed signal is an intracellular or endogenous molecule.

BMC Systems Biology

Great progress has been made in understanding how external cues, provided by signaling molecules emanating from stem cell niches, instruct stem cells to either self-renew or differentiate.

EMBO Journal

However, little is known about the signaling molecules, linking external guidance cues, and cytoskeletal responses, crucial for proper interneuron migration into the Cx.

Cerebral Cortex

This may reflect the complex, mostly indirect induction of gene expression via subsequent signaling molecules by external pro-inflammatory cytokines/ growth factors such as IL-1 β, TNF- α, and TGF- β.

BMC Medical Genomics

Expert writing Tips

Best practice

When discussing cellular communication, be specific about the type of "external signaling molecules" involved (e.g., cytokines, hormones) to provide clarity.

Common error

Avoid using "external signaling molecules" as a catch-all term. Instead, identify the specific molecules involved (e.g., growth factors, neurotransmitters) to provide more precise information.

Linguistic Context

The phrase "external signaling molecules" functions as a noun phrase, identifying molecules that transmit signals from outside a cell to its interior. Ludwig AI provides examples of its use in scientific contexts.

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Ludwig's WRAP-UP

In summary, the term "external signaling molecules" refers to molecules that transmit signals from outside a cell, playing crucial roles in cell communication and biological processes. Ludwig AI affirms its grammatical correctness and common usage in scientific contexts. While the phrase itself is accurate, specificity regarding the type of signaling molecule enhances clarity in writing. Related phrases include "extracellular signaling molecules" and "secreted signaling molecules", offering alternative ways to describe these critical components of cellular communication. Remember to avoid overgeneralization by identifying the specific molecules involved whenever possible.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

extracellular signaling molecules

Replaces "external" with "extracellular", emphasizing the location of the molecules outside the cell.

secreted signaling molecules

Focuses on the secretion aspect of the molecules involved in signaling.

intercellular signaling molecules

Highlights the role of these molecules in communication between cells.

environmental cues

Broader term that includes signaling molecules as one type of environmental influence.

signal transduction molecules

Focuses on the function of transmitting signals rather than their origin.

cell-to-cell communication molecules

Emphasizes the communicative function between cells using molecules.

growth factors

Specific type of signaling molecule involved in cell growth and differentiation.

cytokines

Signaling molecules that mediate and regulate immunity, inflammation and hematopoiesis.

hormones

Signaling molecules produced by glands that regulate distant organs.

neurotransmitters

Signaling molecules that transmit signals across a synapse.

FAQs

How are "external signaling molecules" different from internal ones?

"External signaling molecules" originate outside the cell and transmit signals to the cell, while internal signaling molecules are produced inside the cell to propagate the signal internally.

What's the role of "external signaling molecules" in cell communication?

They act as messengers that bind to receptors on the cell surface, triggering intracellular responses and allowing cells to coordinate functions.

What are some examples of "external signaling molecules"?

Examples include cytokines, hormones, growth factors, and neurotransmitters, each playing specific roles in cellular processes.

What happens if a cell doesn't respond to "external signaling molecules"?

A lack of response can lead to various issues, including impaired cell growth, abnormal differentiation, or failure to activate appropriate immune responses. It depends on which pathways are affected.