Exact(25)
The model can be used for external predictions as it has a high predictive correlation coefficient value of 0.8006.>> The predicted biological residual activity (ΔpIC50= pIC50_experimental- pIC50_predicted) of benzofuran salicylic acid-based derivatives as evaluated by QSAR models is illustrated in Figure 4.
The predictive ability of the model was estimated by cross-validation and by external predictions for new HIV variants; both procedures showed very high correlation between the predicted and actual susceptibility values (Q2 = 0.89 and Q2ext = 0.86).
Moya Greene, the chief executive said she had no option but to push through further cost-cutting, amid external predictions that 3,000 more jobs will go across the company.
External predictions were made on a test set and compared with previously reported models.
Statistically significant models were constructed and validated via the internal and external predictions.
Any chemistry-response relationship model needs to demonstrate not only good accuracy but also reliability of external predictions.
Similar(35)
This external prediction set had an accuracy of 99.44%.
That led to provide more trust about the external prediction of the models.
Externally evaluated final models can be used as a tool for external prediction and virtual screening.
In addition, we show that proteochemometric models improve external prediction capabilities.
Statistical measures generated for both enzymes showed good internal and external prediction.
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