External database entries are generally required to include at least a database identifier and a standard InChI to be included in the UniChem database.
Furthermore, these annotations depend on the external database entries associated with individual Affymetrix sequences, which have been shown to contain frequent inaccuracies 28.
Both for nucleotide and protein database, results of similarity searches are shown in a dedicated section in the classic BLAST output format, including the list of alignments descriptions and details about the pairwise alignments with hits, each hyperlinked to external databases entries.
Transitions between modes are triggered when some state variable exceeds the threshold (state events), after expiration of specified time period (time events) or by external inputs (entry events).
Additional quality checks could also be performed, such as checking whether the two dimensional structure (e.g., in Molfile format) and the chemical formula in an external database entry match the standard InChI.
In such cones, a potentiated sensitivity of cytosolic [Ca2+]i for external Ca2+ entry was observed.
It has been reported that the depletion of the intracellular stores (endoplasmic/sarcoplasmic reticulum) triggers external Ca2+ entry through the activation of the CRAC channels.
In this case, at least one published article in a peer-reviewed journal or the link to an external database entry must be provided.
Annotation fields in SBML are formatted in RDF (the resource description Framework ([ 10]. Each such external link entry is annotated with a qualifier (e.g., "is", "isHomologTo", "isDescribedBy", etc).
Given that the [Ca2+]c oscillations in the low magnesium model are dependent on NMDA receptors and external Ca2+ entry, we determined how each of these factors contributed to ROS generation observed in this model.
