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Although the existence of such unintended effects does not necessarily generate concerns in terms of safety (for human health and/or the environment), it is important to evaluate their extent to validate or discard the application of each genetic engineering product in agriculture [ 10].
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Typically, there are several goals to be achieved in the development of potential biomarkers by glycoproteomics: 1) to identify the glycosylated-proteins, their glycosylation sites, and the glycan compositions; 2) to quantify the glycosylated-proteins and their glycosylation extent; 3) to validate the potential glycosylated-protein biomarkers; and 4) to establish the clinical test method.
Pattern matching was used, to a certain extent, in order to validate these CMO configurations [ 31] and alternative explanations were sought for.
Additionally, HEC-RAS model generated flood inundation extents are used to validate the model performance at fifteen sites that lack FEMA maps.
Given that these quadrupole filters were built using an existing set of 3-D neighbor cases, one needs to validate the extent of their efficacy.
The map of permafrost on the Tibetan Plateau developed by Li and Cheng (1996) was employed to validate the extent of simulated frozen ground in the QTEC in this study.
To validate the extent to which the lead compounds activate p53 pathway and to gain further information of potential other pathways affected, we used transcriptional profiling.
In order to further verify our findings, we also utilized recently published transcription datasets to validate the extent to which UCEs might be transcribed.
Studies with much larger sample sets will provide the necessary statistical power to validate the extent of the downregulation of Wnt-5a in cancer.
Finally, to validate the extent of VEGFR2 expression at mRNA levels, we performed RT-PCR studies and came up with similar results as the overexpression studies.
User logs or similar information used to complete the online form should be maintained and made available on request to the NIEHS in order to validate the extent of use and degree of sharing.
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