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The cluster-defining voxel-level threshold was P<0.001, together with an extent threshold of k≥10 voxels.
Significant clusters were identified using a height threshold of P<0.01 and an extent threshold of P<0.05 with family-wise error corrections63.
To correct for multiple comparisons, a cluster spatial extent threshold was applied by using AlphaSim with 1000 Monte Carlo simulations and contrast-specific smoothness of residual errors.
Group-level statistics were thresholded with a height threshold of Z = 2.3 and a cluster extent threshold of p = 0.05 (corrected).
An extent threshold of 10 contiguous voxels was used in each of the contributing maps.
Across all analyses, the statistical threshold was set at p<0.001 uncorrected with an extent threshold of 8 contiguous voxels.
These PPI maps were then thresholded at p<0.001, uncorrected, with an extent threshold of 10 voxels.
Regions were classified as significant when they exceeded an FDR-corrected threshold of p<0.005, and a cluster extent threshold of 25 voxels.
Significant clusters of activation were determined using the joint expected probability distribution with dual height and extent threshold (p<0.01) corrected at the whole brain level.
Similar(2)
The Monte Carlo simulations masking everything except the amygdalae, led to a minimum cluster-extent threshold of only 1 voxel.
These results were found after applying a voxel significance threshold p < 0.005 and a cluster-extent threshold Ke > 492 voxels.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com