The complementary strategy, i.e. reducing the extent of the procedure, has so far not been pursued systematically, as the extent of an instrumentation is usually defined by the biomechanical demands of the injury itself.
To many, the need for such an extended procedure implies an extent of disease that is usually not amenable to surgical control, and the extent of the procedure exposes the patients to substantial operative risks.
The Canty surgery was the lone surprise, but Coughlin did not know the nature or extent of the procedure.
Furthermore, because the relative differences were analyzed instead of absolute differences the indication for removal of the uterus and consequently the extent of the procedure was therefore considered less relevant.
The histopathology of the SN is crucial, and the extent of the procedure determines the positivity rate [ 47– 47].
A first-class letter from Jacksonville, Florida, in 1888 read simply "Fumigated" and thus did not define the extent of the procedure.
The duration of treatment breaks before and after interventional procedures is at the discretion of the multidisciplinary team at the recruiting site according to the actual extent of the procedure.
In one study in patients after partial hepatectomy substantially higher HGF and VEGF serum levels were found as compared to our data, suggesting a correlation between the extent of the procedure [ 36].
A uniform terminology of the different stages of hypothermia to allow for better comparison as well as a clear definition of the extent of the procedure to be undertaken (e.g., hemiarch/total arch; moderate hypothermia/deep hypothermia) appears essential to facilitate discussion among experts in the field and helps guide future path of modern arch surgery.
A total of five patients did not undergo definitive surgery while participating in the protocol: two non-extremity patients were regarded inoperable due to technical reasons, one patient was diagnosed concomitantly with rectal cancer, one patient declined surgery for the extent of the procedure, and one patient had extensive tumor progression with distant metastasis.
