Except in the case of a written determination that is modified or revoked on account of § 1.6662-4(d)(3)(iv)(A)(1), a written determination that is modified or revoked as described in § 1.6662-4(d)(3)(iv)(A)(2) ceases to be authority on the date, and to the extent, it is so modified or revoked.
But to the extent it is modified, expect the players to hustle: Those that have relied on it must race to unload their only asset, their customer base.
To change this behavior, and allow to re-prioritize services to some extent, the EXP/PF is modified here by adding a new parameter, referred to as Service Priority Index (SPI), as was already done in [32].
The distribution of heat load follows the solar climate to a great extent, while it is modified by maritime or continental influences and altitude.
After NAC, the pathologic extent of disease is modified in 80 90% of patients, whereas pathologic complete response (CR) in both the breast and axilla was achieved in 13 26% of patients (Rastogi et al, 2008).
ChIP-chip results, in accordance with qPCR data, indicate that the locus is modified to a similar extent in both cell types.
We thus analyzed double-mutant combinations to see whether, in these genetically sensitized backgrounds, the extent of Ras/MAPK signaling is modified in vivo.
However, the extent of site specific phosphorylation is modified by subcellular localization and hence stimulus specific activation that is dependent upon localization would be a useful avenue for future work [ 38].
These experiments have revealed the large extent by which the proteome is modified and how much PTMs may be modulating protein function.
To determine the extent to which the proteome is modified upon ERK8 depletion, we metabolically labelled cells with a GalNAc sugar analogue, FLAG-GalNAz (Laughlin and Bertozzi, 2007).
The co-operative nature of the GK GKRP interaction and the extent to which this interaction is modified by physiological ligands and GKAs is further illustrated in Hill plots (Supplementary Figure S9 at http://www.biochemj.org/bj/459/bj4590551add.htm).htm
