The speed and the extent of this transition were totally unexpected.
Comparison of the PTEN structure from the atomistic simulations with the crystal structure suggests a degree of conformational change corresponding to a rotation of ∼10° of the PD relative to the C2 domain, although more extended simulations may be needed to capture the full extent of this transition.
As shown by a precise analysis of the dynamic mechanical data in terms of activation energies and entropies, the extent of the β transition strongly depends on the role played by the crosslinks.
We show that by controlling the extent of phase transition the simulations can be brought into close agreement with experimental data from the literature.
Further, the bias patterns varied among the SNP types, e.g., the extent of the biases for transition SNPs (A/G and C/T) was much stronger than those for transversion SNPs (A/C, G/T, A/T, and C/G).
The transitions of FPR, PPV, and μ P − value from poor to good performance were not smoothed by noise to the same extent as the transition of the NE.
Although it is well known that Kerala has moved from younger age group mortality to older age groups, the extent of transition to the oldest age group (delayed degenerative disease pattern), and its major causes of death remain unknown.
With this method, the extent of phase transition (freezing/thawing) was measured with the TDR module; and the corresponding thermal properties were measured with the TPT module.
Depending on the extent of health transition, cancer mortality as a proportion of total mortality differed substantially by region, from less than 5% in AfrE to approximately 30% in WprA sub region.
However, both the extent and the kinetics of the transition from elongating to arborizing growth significantly differed in embryonic and postnatal neurons (Figure 4A, B; Chi square test, P<0.001 from 5 DIV on).
