Sentence examples for extent of the functional from inspiring English sources

Binding of Rfx3 to Abcc8 or voltage-dependent Ca2+ channel genes has not been reported, and although Rfx6 and Rfx3 might coregulate other targets genes, the extent of the functional redundancy of both transcription factors in β cell function and insulin secretion cannot be evaluated, as the phenotype of mice with a deletion of  Rfx3 in adult β cells has not been described.

We also observed that SC-NES cells produce an amelioration of locomotor deficits and that the extent of the functional improvement depends on lesion severity.

We did not re-iterate the invention of tumor-specific antigen; however, we did provide a suitable computational platform that clinicians and researchers need for measuring anatomical volumes and spatial extent of the functional information of tumors accurately, robustly, and longitudinally - and within seconds (for heightened efficiency).

The extent of the functional diversification within the trihelix family across different species is a topic for further investigation.

Despite these limitations, the results showed the importance of restorative intervention in decrease the prevalence, severity and extent of the functional and psychosocial impact of oral disorders.

The extent of the functional reorganization that takes place therefore appears to be proportional to the degree of damage to the hippocampus.

9 The severity of PEI is variable and determined by factors such as the extent of resection, the functional capacity of the remaining pancreatic tissue, the influence of the underlying disease and changes in anatomy resulting in alterations of normal intestinal physiology, transit and motility.

To determine the extent of this functional link, we decided to study the effect of TRIM32 on another known substrate of the laforin-malin complex, namely the AMP-activated protein kinase (AMPK).

Investigation of other NCL genes [the Dictyostelium genome encodes orthologs of CLN1-5, CLN7 and CLN10-14 (Hubet et al., 2014)] will reveal the extent of this functional overlap.

There were no significant differences in hemodynamic responses related to the extent of the cardiac functional capacity.

It has investigated the "fit" between the size of the administrative boundary controlled by city governments (usually led by a mayor, city manager or governor) and the extent of the "wider functional metropolitan" area of 35 cities and undertaken a detailed analysis of the governance arrangements of complex cities like London, Delhi, Bogota and Tokyo.