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We also determined more precisely the extent of the fragment rearranged between the human and pig genomes.
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We have pinpointed the regions to be analyzed as potential enhancers by the presence of a human-Fugu conserved sequence element, but the extent of the fragments included as CNEs was defined from human/mouse comparison.
In the case of a fracture of a single bone, as the femur, which has been broken by direct injury, the extent of the overlapping of the fragments is from the nature of the injury and the mode of causation of the fracture usually much less.
The screening analysis was performed on each fragment separately thus a pattern motif must to match completely in the extent of analyzed fragment.
This applies equally to fractures produced by direct injury, the resistance to replacement varying with the extent of overlapping of the fragments, the amount of extravasation of blood, the laceration of soft parts and the consequent inflammation.
Short double-stranded DNA fragments affect the methylation extent of regulatory fragments and/or coding portions of the homologous genes, and thus change their expression level.
The extent of fragment dislocation was measured in mediolateral and craniocaudal direction.
Overall comparisons between the R1 R7 structures determined here with the same region in the intact vault particle (Tanaka et al, 2009) showed a good superimposition of the central domains, from R3 to R6, but different changes in the relative positioning of domains R1, R2 and to a lesser extent R7, affecting the relative curvature of the fragment.
Subtracting these numbers from the PCR fragment sizes indicate the extent of the isolated flanking genomic DNA.
For sample C2, the cDNA was amplified in two fragments to identify the extent of the genomic deletion.
It is not possible to include the full extent of the known interaction of APP and its proteolytic fragments here and further interactions may yet be discovered.
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