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In addition, we tested whether or not epsin overexpression also suppresses the aux mutant phenotype, and if the extent of suppression would be increased by by co-overexpressing clathrin heavy chain and epsin.
Although force-expression of miR-34a suppressed the expression of DLL1 and NOTCH1, the extent of suppression was higher in DLL1 than NOTCH1 in both cell lines.
To determine whether the TEOAE amplitude changes with and without contralateral noise, paired t-tests were used, and differences in the extent of suppression between the patients and controls were compared using the Mann–Whitney U test.
The ratio between the cold downward flow and the hot upward flow is varied between 0 and 0.15 to predict the extent of suppression of the hot upward flow within the chimney region for various bypass flow ratios.
The extent of suppression of Th17 differentiation was regulated by the strength of TCR and co-stimulatory signals.
Using a generalized linear model (GLM), neither the type or number of APC nor time in culture were shown to influence the extent of suppression, even though the strength of TCR stimulation almost reached statistical significance (p = 0.057).
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To clarify the different extents of suppression by scSUI1, we added the sentence: "Introducing scSUI1 also mitigated their Slg- phenotypes, slightly for - R225K and substantially for - E144R".
We found that, similarly to the suppression of recombination frequency, the extent of DSB suppression around centromeres appears to be directly proportional to chromosome size.
(11) Because the extent of the suppression by IGF1R inhibition is modest in comparison to that caused by miR-493, it is likely that an unknown target gene(s) plays important roles on the inhibition of metastasis by miR-493.
Although this phenomenon is conserved, the extent of this suppression varies because mouse cells suppress recombination between sequences with 1.4% divergences to a greater extent than both human cells (LaRocque and Jasin 2010) and Drosophila (this study).
MYC-driven liver cancers show a dramatic suppression of let-7; other tumor or tissue contexts may not share this extent of let-7 suppression.
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