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At the sequence level this is reflected in the extent of sequence divergence that can be observed for individual repeats.
The extent of sequence divergence between DRB1 alleles representative of ESG1 and ESG2 is demonstrated in Figure 1.
However, the true extent of sequence divergence is not captured by multilocus RFLP analysis.
We therefore used uncorrected p distances for deduced amino acid sequences to measure the extent of sequence divergence.
Such studies have been severely hampered by the great extent of sequence divergence among vertebrate and invertebrate PGRPs.
As stated above, D and F* are more sensitive than D* to the extent of sequence divergence, and thus to balancing selection.
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Data reported here also indicate high levels of sequence divergence within Glyphorynchus.
In addition, when there is a large amount of sequence divergence between two nodes in a tree (site saturation) the accuracy of d S, and to a lesser extent d N, is greatly reduced.
For duplicated genes, structural divergence and nucleotide substitution are two major types of sequence divergence [ 36].
This would produce upwardly biased estimates of sequence divergence.
TSLP exhibit a high level of sequence divergence.
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