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Not only are the genes that are repressed in M vs G2 largely the same as those repressed in M vs G1, the extent of repression is very similar too (new Figure 2D).
In addition, few LIF-repressed genes (Lifrep genes), with the extent of repression less than 2- fold, were retrieved 24 h after LIF withdrawal (Ddh2, Mtss1, Chd8 and ESTs), and no repressed genes were identified after 48 h of LIF starvation.
The crackdown comes as the Guardian launches an online database that catalogues the extent of repression by the Iranian authorities.
Although there has been debate about the extent of repression under his leadership, the Horthy government was authoritarian and nationalistic, not fascist.
Moreover, leucine availability-induced alterations in Sestrin2 phosphorylation correlated temporally and dose dependently with the activation state of mTORC1, there being a reciprocal relationship between the degree of phosphorylation of Sestrin2 and the extent of repression of mTORC1.
Marie only learned of the extent of repression used to quell the 1907 Romanian Peasants' Revolt once it was too late to intercede.
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Our analysis of public Tup1p occupancy and activity data suggests that different subsets of Cyc8 Tup1 repressed genes may exist, subject to different extents of repression by the various overlapping mechanisms proposed for Cyc8 Tup1 activity.
The fact that we observed very similar extents of repression of all three MHC class I forms (Kk, Ld and Dd) as well as of β2-microglobulin suggests that MeCP2 probably does not act directly on the promoters of the various loci encoding MHC class I, which are not identical.
Δ[Vrn1] is repressed under high temperatures and the extent of this repression is dependent on variation (allelic and/or copy number) in Vrn1 genes.
Had Trotsky won the struggle to succeed Lenin, the character of the Soviet regime would almost certainly have been substantially different, particularly in foreign policy, cultural policy, and the extent of terroristic repression.
Interestingly, the extent of the repression was much weaker than that in S. cerevisiae at 30°C (Figure 3c).
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