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In the absence of absolute quantitative SPECT characterization, relative image intensity ratios were constructed to quantify both magnitude and volumetric extent of liver function.
The TLF represents a functional liver mass that takes into account both the density and volumetric extent of liver function in patients.
② Emptying of the stomach is delayed: It has been reported that gastric half-emptying of liquid food is delayed in patients with liver cirrhosis, and the function of gastric emptying is influenced by the extent of liver function damage[ 16, 17].
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The discrepancy in prognostic performance of the AJCC staging system is not unexpected because the AJCC system evaluates tumour extent only, regardless of liver function reserve, which is another essential factor affecting clinical outcome of patients with HCC.
However, the intermediate group comprises a wide spectrum in terms of liver function and extent of tumour, and this may explain the large differences in survival reported for individual series [ 4].
Finally, liver function may be relevant in studies of microbial translocation as the liver may remove incoming bacteria from the portal circulation to varying extents and the inclusion of markers of liver function therefore advisable.
Preoperative prediction of liver function is important to provide a gauge of the hepatic functional reserve, which determines the maximum extent of hepatectomy possible to avoid postoperative liver failure.
The condition implies a loss of liver function, and it is a fundamental assumption that the extent of this loss is important for survival.
This study showed that the level of AFP protein in liver tissue gradually increased with the deterioration of liver function and it reflected degrees of the liver cell proliferation to a different extent.
John Chambers and colleagues report a genome-wide association study for markers of liver function.
Liver cell transplantation and bioartificial liver may provide metabolic support of liver function temporary and are prospective treatments for patients with liver failure.
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