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The dN/dS ratio indicates the extent of evolutionary divergence of DNA sequences.
To identify miRNAs that regulate hPGRN expression, we used an miRNA target prediction program that considers complementarity, target site accessibility, and the extent of evolutionary conservation [28].
Although it is known that salt tolerance is a quantitative trait determined by multiple and complex genetic interactions [7] [9] and that plant responses to salinity involve changes in the expression of thousands of genes [2] [3], [10], we know little about the extent of evolutionary conservation of molecular networks that determine salt tolerance.
However, the full extent of evolutionary responses to fishery selection in natural populations may be complex.
Therefore, we compared the extent of evolutionary conservation between groups as judged by the proportion of significant BLAST hits.
(A ) Boxplot showing the extent of evolutionary conservation of transcriptional programs for all orthogroups or those with RAP domains.
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A fuller understanding of the nature and extent of these evolutionary changes can best be achieved in the context of the evolutionary history of salmon and the dynamic environments in which they evolved.
Although the extent of the evolutionary impact of HGT is still under debate [ 22- 24], it is generally accepted as an important evolutionary process in microbial species [ 19].
But we now see that a great extent of genetic evolutionary change is under biological control.
Not all homeobox genes are ancient, however, and the extent of their evolutionary conservation varies considerably.
While some instances of functional compensation have been observed in Drosophila, the function of common binding and the extent of its evolutionary conservation is not known.
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