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The times of dilution (TOD, the extent of decreasing in MIC value) were determined up to 16 for the combined MIC.
In vitro experiments showed a direct correlation between the extent of decreasing GSH levels and impaired cell viability (Suppl. Fig. 1), proving functionality and specificity of our approach.
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The integration numbers of NTS-based expression cassettes, ranging from one to ∼30 copies, showed a proportional increase with the extent of decreased expression of the auxotrophic markers.
The extent of decreased ANA level was correlated with the inhibition of OAZ expression, the reduction of IL-21 level and the elevation of CCL2 level.
The extent of decreased attenuation was inversely correlated with FEV1 (rs = −0.26; P = .06), as was consolidation (rs = −0.3; P = .05).05
The association between extent of decreased attenuation and a composite score of the extent of small and large airway plugging on HRCT ("secretion score") was weaker but statistically significant (rs = 0.48; P < .001).001
The molecular titration of FIH by ARD-containing proteins likely determines the threshold (i.e., extent of decreased oxygen tension for activation of HIF-1α) (Schmierer et al. 2010).
More recent studies could demonstrate an association of early age at first drinking and the extent of decreased gray matter volumes in the cerebellum, brainstem and frontal regions using voxel-based morphometry (e.g. [ 11]).
In contrast other studies could demonstrate an association of early age at first drinking and the extent of decreased gray matter volumes in the cerebellum, brainstem and frontal regions using voxel-based morphometry [ 11].
> -wrap-foot> On HRCT, the extent of decreased attenuation was strongly correlated with extent of bronchiectasis (Spearman correlation coefficient, rs = 0.80; P < .001) and with other features indicating large airway pathology (severity of bronchial wall dilatation (rs = 0.80; P < .001) and bronchial wall thickening (rs = 0.73; P < .001).001
PHB hydrolysis decreases the molecular weight of final products, the rate and extent of decrease being dependent on the degradation mechanism.
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