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However, it is still unclear whether or to which extent cells in fact do undergo a complete conversion of cell type or show only transient changes in cellular morphology and protein expression patterns that are supportive of a migratory phenotype.
To verify double labeling throughout their extent, cells were examined in orthogonal planes.
In Fig. 4, the histogram of fluorescence intensities indicated that almost the same extent cells (94% vs. 95%, respectively) were stained by FITC-labeled TP5 and mAb-DR FITC above the background, with an approximately 3 orders of magnitude increase in mean fluorescence intensity (MFI).
For decades, it has been a subject of research whether (and to what extent) cells actually behave like polymer gels.
CD68 staining could clearly identify cells with an amoeboid morphology, and to a lesser extent cells with a ramified morphology.
As such, we examined trade-offs between pairs of near and far environments to test to what extent cells can cope with environmental variability.
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Adhesion to HELPs stimulated at a different extent cell proliferation and differentiation, the expression of Myosin Heavy Chain and the fusion of aligned fibers into multinucleated myotubes.
Limited data are available on duration of varicella vaccine-induced protection among adults and to what extent cell-mediated immunity (CMI) and antibody avidity contribute to protection.
In the necrotic region, tumor cells were more heterogenous with high cellular polymorphism; severe damage was seen with nuclear pyknosis, cell necrosis, and cell lysis; and to some extent, cell fragments were also observed.
In parallel to the experimental studies designed to address these issues clinical trials are under way and should hopefully allow assessing to what extent cell transplantation may improve the outcome of patients with heart failure.
Pharmacological inhibition of PKCs and PKDs using chemical inhibitors revealed to some extent cell death in the differentiating cultures.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com