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The cytotoxic/cytostatic activity of macrophages is, to a great extent, attributed to the up-regulation of inducible nitric oxide synthase (iNOS) and production of nitric oxide (NO).
At early stages post treatment (e.g., 12 h), when cell viability is not obviously disturbed, the antiangiogenic activity of MLN4924 is to a large extent attributed to the accumulation of RhoA, a CRL substrate, since knockdown of RhoA markedly rescued MLN4924-induced anginhibitionhinhibition
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We attempt to speculate that these specific motifs may by some extent attribute to the subfunctionalization or neofunctionalization of the duplicated genes during subsequent evolution processes.
Population movements in the millennia following this initial settlement are thought to have greatly influenced the genetic makeup of current inhabitants, yet the extent attributed to different events is not clear.
Accordingly, the insignificant prolongation of overall survival by 2.3 months in wtKRAS patients over the mutated KRAS subgroup may be to some extent attributed to subsequent anti-EGFR therapy (Table 1).
This might indicate that the influence of area deprivation can be, to a certain extent, attributed to individual socioeconomic factors.
We assumed that high expansiveness of S. oryzae in cereal crops may be to some extent attributed to highly active digestive enzymes, especially amylases, synthesized by this insect.
The first years of the 1990s bear the mark of the Curriculum Committee's preoccupation with cultural continuity and can to considerable extent be attributed to the influence of a conservative-led center-right government (1991 1994) and a general sense of insecurity in the wake of European turmoil and economic recession.
Boysen-Hogrefe and Groll (2010) show that the so-called German Job Miracle and the intensive use of adjusting hours can only to a minor extent be attributed to the German Kurzarbeit, which is quantified by Fuchs et al. (2010) to a third of working-time reductions62.
We believe that the above observations are all correlated with each other confirming that annealing of a bare ZnSe surface can induce an imperfect <011>-oriented trench/groove structure to a certain extent being attributed to the minimization of the surface energy.
And while I would concede Ning's remarkably high conversation rate can, to a certain extent, be attributed to the fact Rosenthal turned the proverbial shoebox into something more closely resembling an iron-clad locker, I would suggest something else is at play here that's contributed to Ning's remarkable retention rate: the perception of value.
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CEO of Professional Science Editing for Scientists @ prosciediting.com