Sentence examples for extent alterations from inspiring English sources

Taubert and coworkers27 moreover noted that it is often unclear whether or to which extent alterations in brain structure are linked with individual learning success.

Drosophila stem cell populations show defects in replicative homeostasis during aging in the gut [ 45, 46] and gonads [ 47- 50], however it is currently unknown to what extent alterations in stem cell function might limit adult Drosophila life span.

In particular, we aimed to establish to what extent alterations in cortical and/or trabecular bone contribute to the increased bone mass observed in HBM, to characterise changes in bone structure underlying these findings, and to determine to what extent altered age-related bone loss contributes to the observed phenotype.

Large, carefully designed studies are needed to better estimate the extent of alterations in neurometabolites.

To determine whether grade of varicocele determines extent of alterations to semen quality in adolescents.

However, in migraine the extent of alterations was more focal, restricted to the frontal white matter.

The data was smoothed using a three-clone sliding window and CGH plotter [29] was used to identify the extent of alterations using a segmentation constant of 7. Log2 ratios for two continuous BAC clones outside the threshold ranges were classified as copy number changes including gain (threshold +0.25), loss (−0.25), amplification (+1) and homozygous loss (−1).

There have been several attempts to estimate the extent of alterations in tumor genomes.

To what extent these alterations reflect distinct pathophysiologic processes in uremia warrant further investigation.

To what extent these alterations represent adaptive or maladaptive immune processes is not well understood and needs further investigation.

How does sphingolipid-associated autophagy occur and to what extent do alterations in autophagy contribute to disease phenotype?