Sentence examples for extensively upregulated from inspiring English sources

RGC-32 was found in the present study to be extensively upregulated in p63 knockdown cells.

For both types of cells, GLA upregulated the expression of miR-200c more extensively.

MiRNA-10b has been extensively studied in several pathologies and miR-10b is highly upregulated in human GBM compared with normal brain tissues.

Although the factors that regulate S100P have not been studied extensively, DNA microarray studies have included S100P among panels of genes upregulated by oestradiol (Terasaka et al, 2004), progesterone (Bray et al, 2005), and HER2 overexpression (Mackay et al, 2003).

miR-21 is an extensively studied oncogene capable of targeting multiple tumor suppressor genes, which is upregulated in chemoresistant colon cancer stem cells.

Genes upregulated during Fe deficiency-associated stress in graminaceous crops have been described extensively (Bashir et al. [2010]; Ishimaru et al. [2009]; Ishimaru et al. [2011b]; Kobayashi et al. [2005]; Nagasaka et al. [2009]; Negishi et al. [2002]; Nozoye et al. [2007]), and our microarray data are consistent with those of previous reports.

As the most extensively studied and clinically validated gene for therapeutic utility in T2DM, PPARγ can be upregulated by thiazolidinediones and anthocyanins to improve insulin sensitivity and glucose uptake in human adipocytes and animal models of diabetes (4).

Among the numerous genes known to be upregulated in the hippocampus following spatial learning, members of the immediate early gene (IEG) subfamily have been extensively studied following maze learning.

This extensively studied 22-nucleotide miRNA (encoded at human chromosome 11q24.1: 5'-ucccugagacccuaacuuguga-3' [Genbank: NR_029671.1]) was first shown to be upregulated in both stressed and differentiating mouse and human neurons, and has since been implicated in mammalian neuronal development, brain cell signaling functions and degenerative disease [ 45, 49].

Some sialidases are upregulated in lung fibrosis.

WRKY53 was upregulated only by ASGV.