Sentence examples for extensively induced from inspiring English sources

The formation of GFP-LC3-labeled puncta, representing association of LC3B-II with autophagosomes (27), was extensively induced in cells exposed to CSE (Fig. 2C).

Such alterations are secondary to the activation of chemosensitive nociceptors by inflammatory mediators, which are extensively induced by snake venom injection [ 33– 33].

The TUNEL staining revealed that apoptotic cell death was extensively induced in LNCaP tumours treated with simultaneous castration and mitoxantrone compared to tumours treated with the other schedules.

Similarly, in cardiac stem cells, Ref-1 inhibition followed by H2O2 treatment extensively induced the levels of intracellular ROS, resulting in significant elevation in cardiac differentiation and apoptosis.

Our previous study indicated that in vivo NaF treatment to rats extensively induced intracisternal granules in the ER lumen and autophagosomes in the cytoplasm of the exocrine pancreas cells, and this autophagy activation was associated with activation of the PERK-eIF2α-CHOP pathway but not with activation of the Ire1-XBP1 pathway (Ito et al., 2009).

Among the 95 genes assessed, those extensively induced by gp120Bal were CXCL11, CXCL9, and CXCL10, IL-27, and iNOS, a profile typical of an M1 pro-inflammatory macrophage response, and also IL-1α, IL-1β, TNF-α, CCL2, and PG E synthase, which have all been shown to play a key role in neurodegeneration and pain.

Although Onishi et al. (2009) argued that because no significant surficial change was present through the 2007 earthquake, the southeastern area is unaffected by the mud volcano activity, the presence of subsidence found in this study may suggest that the mud volcano affects the surrounding area extensively, inducing subsurface lateral migration of fluid mud.

Within macrophages, AIEC strains survive and replicate extensively without inducing host cell death and induce the release of high amounts of TNFα.

Though voluntary wheel running (VWR) has been used extensively to induce changes in both behavior and biology, little attention has been given to the way in which different variables influence VWR.

The main autoimmune epitope of P2 locates at residues 58 73 [58], and a peptide corresponding to this region has been been used extensively to induce and study the animal model of GBS, EAN.

Complete Freund's adjuvant has been used extensively to induce arthritis in rodents including mice [ 21- 23].