Sentence examples for extensively established from inspiring English sources

In the last decades, it has been extensively established that multicellular spheroids represent an efficient model to validate effects of drugs and treatments for human care applications.

Therefore it comes as no surprise that the approximate controllability for various control systems has been extensively established in the literature; see [3 8] and the references cited therein.

We now embark on a randomized, blinded, sham-controlled school environmental intervention trial, built on our extensively established school/community partnerships, to determine the efficacy of a school-based intervention to improve asthma control.

Crosstalk or reciprocal regulation between hormone-dependent pathways, including ERα- and AR-mediated signal transduction, and NF-κB signaling has been extensively established at multiple signaling nodes [43], [44], [45].

Therefore, investigations focused on inhibiting either excessive generation or hyperactivity of BACE1 are extensively established on account of alleviating the symptoms or even eradicating of the disease in early stage.

Given that the lack of P. falciparum-encoded microRNAs and microRNA processing machinery has been extensively established, we did not anticipate microRNA sponge roles for P. falciparum circRNAs [ 39, 40, 58].

Literature extensively establishes the mediating role of burnout when investigating healthcare providers' turnover within the hospital and PHC setting, as the level of burnout presents as a predictor of job satisfaction [ 12, 29, 38].

David took this advice, but conscious of her inexperience as a writer she kept her own prose short and quoted extensively from established authors whose views on the Mediterranean might carry more weight.

From the founding of the firm, Mr. Tomita traveled extensively to establish Tohmatsu's presence abroad, beginning in San Francisco and quickly spreading throughout the Americas, Europe and Asia.

The scenic beauty estimation method (Daniel and Boster, 1976) and its experimental procedures have been used extensively to establish relationships between a number of factors and respondents ratings of the scenic beauty of a variety of landscape stimuli, mostly photographs.

Heat cured geopolymer binders have been studied extensively to establish their mechanical behaviour under quasi-static loading conditions and it has been found that they are capable of achieving comparable and in some cases better properties than ordinary Portland cement (OPC).