He dealt extensively with the difficult North-Korean and Iranian issues, as well as the more satisfactory cases of South Africa, Argentina and Brazil.
The windscreen of the metaphorical car that the commission is trying to drive has been cracked so extensively that it's difficult to see anything clearly through it.
While specific GSTs have been extensively characterized, it is difficult to compare members of different classes, and there has been little investigation in this area.
Although substitution of aluminum into iron oxides and oxyhydroxides has been extensively studied, it is difficult to obtain accurate incorporation levels.
However, wide variations of Hb levels among cancer patients, or even the general population, have been extensively reported, making it difficult to diagnose anemia solely based on a single measurement of Hb level at baseline.
The building was so extensively damaged that it was difficult to bring out bodies, he said, and it will have to be repaired before that work can end.
However, the statistical behaviour of this parameter has not been extensively studied and it is difficult to understand its true meaning.
The cells respond extensively to environmental factors, are difficult to maintain in primary cultures, and have a short lifetime.
This explains why obtaining computer-assisted instruction materials used extensively in medical education is difficult to achieve [ 8].
