Exact(2)
In this study, we examine the impact of drug-resistant mutations in HIV-1 protease on substrate recognition and demonstrate that most primary active site mutations do not extensively contact substrates, but are critical to inhibitor binding.
The structures show that two MADS domains extensively contact each other, but mutagenesis data indicate that also other parts of the MIKC proteins contact each other.
Similar(58)
The transverse process is fused to the sacral rib, forming a single complex that extensively contacts the ilium.
The medial surface of the ectopterygoid extensively contacts the pterygoid between the vomeropalatine and ectopterygoid rami (Figure 25B).
As a foreign correspondent for the Washington Observer he travelled extensively, fostering contacts with exiled royalty in Europe.
More commonly, cadherins appeared to distribute extensively at contacts between cells, as if junctions represented carpets of homoligated cadherin complexes.
Furthermore, semiconductor device processing involves extensively with surface contact, cracking, film delamination, and propagation of dislocations, which may degrade the performance of these devices.
Compared with the wettability of liquid titanium on the calcia-stabilized zirconia ceramic substrate in the gravity field, the electromagnetic field can decrease extensively the equilibrium contact angle from 103° to 31°.
Brf2 contacts extensively the phosphate backbone of the DNA and establishes sequence-specific contacts with both the upstream and downstream TATA flanking regions.
Moreover, free-roaming behavior in extensively managed pigs favor contact with rodents and the probability of ingestion of infective cysts contained in their tissues [ 59, 60].
With the exception of tobacco mosaic virus, relatively few viruses or viroids are spread extensively in the field by contact between diseased and healthy leaves.
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