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DOX is extensively bound to cardiolipin and a pool of cytochrome c is also bound to cardiolipin in the membrane.
7 Sitagliptin is not extensively bound to plasma proteins.
However, ritonavir was extensively bound in lysates from human hepatocytes (fu = 0.024 ± 0.006).
Tazarotene and tazarotenic acid are extensively bound (more than 99%) to human plasma proteins.
Although ZNM is only 40 60% plasma protein bound, it is extensively bound to erythrocytes [ 2, 3].
Since most NSAIDs are extensively bound to plasma proteins, they may displace other drugs from binding sites or may themselves be displaced by other agents.
Similar(47)
MeHg extensively binds to intra- and extracellular proteins by the formation of cysteine complexes.
Oseltamivir carboxylate is not extensively protein bound and, thus, immaturity of plasma protein levels does not impact on VD [27].
Spirochetes incubated in EDTA-treated NHS were washed extensively and bound proteins were eluted.
The column was washed extensively and bound proteins were eluted by reduction of the biotin conjugate.
The beads were washed extensively and bound protein then incubated with Precision protease, releasing species of ∼70 kDa and ∼150 kDa (by SDS PAGE).
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