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Once estimated, I show how the liability estimates can then be used to search for likely functional non-synonymous deleterious variants that influence addictive behavior by exploiting the extensive whole genome sequence information that we have for this study.
Increased functional diversity results from extensive whole gene duplication in some cases, creating gene families, whereas in other cases it evolves through alternative splicing.
An extensive whole genome analysis from the OCCAM group detected DCK, PAPSS2, SIRT2 and TRIM44 as potential prognostic biomarkers on the transcriptional and immunohistochemical level (Peters et al, 2010).
Michiel Van Bel (Ghent University, Belgium) presented an ensemble method intended to detect orthologs in plant species combining different orthology inference methods a notorious challenge due to extensive whole genome duplication and paleopolyploidy.
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Some outstanding examples incorporating extensive whole-tone harmony are Debussy's "Voiles" (1909; Préludes, Book 1, No. 2) and "Cloches à travers les feuilles" (1907; Images, 2nd series, No. 1), as well as Dukas's opera Ariane et Barbe-Bleue (1907).
Although this study profited from the extensive whole-genome sequence data, no proof was provided of the existence of Y-chromosomal DUX copies in non-human primates.
The extensive whole-genome data also permitted us to delineate clear patterns of geographic dissemination of derivative subclones.
We analyzed extensive whole-genome sequence data from a large collection of clonal and nonclonal pathogenic bacterial species to compare the factors contributing to genetic variation between them.
This study is the first to use extensive whole-genome sequence data from global Haemophilus isolates to identify and design a highly accurate molecular assay targeting H. influenzae.
Here, we present extensive whole-genome resequencing analyses for 55 pigs of five breeds: Korean wild boar, Korean native, Duroc, Landrace, and Yorkshire.
More extensive whole-genome sequencing studies and other subtyping methods, such as multiple-locus variable-number tandem repeat analysis, hold promise for providing a better understanding of the relationships between isolates.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com