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In addition, lung appeared to be a site of extensive virus replication.
This led to high confidence in the prevalence estimates, but due to the bias caused by the sampling of certain bird species during the outbreak, more extensive virus circulation cannot be excluded (Figure 5, A).
Rapid and extensive virus spread within the SWIO islands was demonstrated for three CMG complex species.
In contrast, all other nucleotide positions remained unchanged during the extensive virus propagation including the heterologous E2 sequences.
To investigate whether the emerging PRRSV was the causative agent of the pandemic diseases on swine farms, an extensive virus survey was conducted.
This was based on the assumption that, in most instances, human cases were indicative of a relatively extensive virus circulation, i.e., agro-ecological conditions permitting an easy transmission.> Data on human cases of HPAI H5N1 were compiled from WHO (2009).
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However, the vast majority of cells showed extensive virus-induced cytopathic effect (CPE) at 72 h post infection (h.p.i).
In this regard, a recent study of oncolytic ONYX-015 in colorectal cancer patients demonstrated that an early increase in tumor volume that followed viral treatment occurred because of extensive virus-induced necrosis of tumor masses and not continued tumor growth.
While weak selective pressure on the envelope (E) protein gene of some dengue viruses is evident (19 ), the most extensive changes in virus genotypes appear to be due to recombination or to possible genetic bottlenecks (16, 17, 20 ).
In summary, the extensive intermingling of virus from multiple blood tissues with virus from the lung, the lack of a macrophage-tropic motif or signature site in the V3 region (even in purified lung macrophages), and evidence for X4 viruses in both blood and lung, are consistent with a model in which virus in the blood and lung are frequently exchanged.
If he were malicious, he could do extensive damage uncork a virus, plant a logic bomb, joyride through their servers and trash their data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com