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Despite these extensive temporal and spatial fluctuations, the overall architecture of the monomeric mutant protein resembles that of wild-type GB1 and not the monomer unit of the domain-swapped dimer.
We performed, for the first time, extensive temporal and spatial expression analyses of RP-associated splicing factors, Prpf3, Prpf31 and Prpc8, and other splicing factors, Prpf4, U1-70K protein and SF3a as well as snRNAs in mice in order to gain information on tissue specific expression and developmental regulation of the splicing machinery.
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We must acknowledge the rich and extensive literature discussing temporal and spatial bifurcations in Wilson Cowan (and W C-like) mean-field neural models.
This insight follows from an extensive characterization for the temporal and spatial clustering of firing events from in-vivo calcium recordings.
Additionally, it potentially limits the ability of researchers to obtain extensive and thorough data on temporal and spatial variability in nesting behaviors.
A prolific expansion of sequencing data, combined with new experimental and computational methods in genomics and transcriptomics, have spurred an extensive exploration of chromatin regulation, and the temporal and spatial organization of the RNA transcriptome.
For these reasons, the context of these recordings needs to be provided by subdural electrocorticography, which has lower temporal and spatial resolution, but more extensive coverage, and critically, is used in many neurosurgical centres worldwide.
Regarding the complicated temporal and spatial regulation of Ca2+ signaling in migrating cells, we would expect extensive interactions between Ca2+ and other signaling modules during cell migration.
So, over time, we say the temporal and spatial resolution increased.
It is a combination of temporal and spatial induction.
The theory behind besieging a population is to annihilate temporal and spatial domains, and by so doing slowly strangulate a people's will.
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