While ischemia, hypoxic hypoxia, and carbon monoxide (CO) have received extensive study designed to characterize mechanisms by which they disrupt cochlear function, little data are available concerning cyanide's potential to disrupt auditory function.
A more extensive study specifically designed to resolve this discrepancy has now shown that recombinantly-expressed human aspartoacylase is not glycosylated, but is still fully functional and stable even when produced from a bacterial expression system.
The material for this article was drawn from a more extensive doctoral study, designed to investigate intentional communication in this population, through the use of songs in music therapy.
To quantify the effect of distortion on observed GWAS outcomes, we ran an extensive simulation study designed to mimic patterns of LD in European Caucasian populations.
We perform an extensive study for realistic design of a phase-matching mechanism for multiple-cavity systems and demonstrate its experimental feasibility using a double-cavity system.
The construction in Portugal of a relatively long and slender footbridge prone to pedestrian-induced vertical and lateral vibrations motivated an extensive study for the design and implementation of a control system based on a set of lateral and vertical tuned mass dampers (TMDs).
Several limitations were identified, including a lack of randomization, small sample size, inadequate follow-up, and extensive study protocol and design differences.
ST provided the laboratory resources, gave extensive input on study design, and was instrumental in interpreting the results.
This review provides an introduction to such considerations with the aim of generating more extensive discussion for study design, assay performance, and regulatory approval in the process of translating new proteomic biomarkers from discovery into cancer diagnostics.
Despite the fact that most CTC assays are highly specific and sensitive, there are not so many extensive studies especially designed to compare their efficacy when using the same clinical samples.
