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However, in spite of extensive studies aimed at understanding the biochemical and structural basis of the PDZ inner-workings, PDZs have proven difficult to place into discrete functional categories [10].
In spite of extensive studies aimed at defining the assembly of NEMO, its oligomeric state still remains a matter of some controversy.
Our understanding of muscle physiology has evolved through the years by extensive studies aimed at identifying molecular and physiological mechanisms involved in normal muscle function and disease.
In the last two decades, extensive studies aimed at improving understanding of intrinsic signaling pathways that control execution of apoptosis in cancer cells were undertaken.
Some strains of L. acidophilus and L. johnsonii are commercialized as probiotics and they have been subjected to extensive studies aimed to infer the mechanisms governing their beneficial health effects.
Extensive studies aimed at identifying specific IsdB/H residues that interact with Hb have focused on the conserved aromatic residues within loop 2, a structural "aromatic motif" which appears to be only present in the Hb-binding NEAT domains.
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More extensive studies aiming to evaluate the heterogeneity of HCV genotypes in samples collected from the general population of the country are needed.
More extensive studies aiming to evaluate the prevalence and heterogeneity of HCV genotypes circulating in the general population of the country are needed.
A piloted questionnaire was developed by the first author, for an extensive study aiming at measuring the PMU's students perceptions of different aspects of studying at medical school.
In the present paper we report one of the first extensive proteomic studies aimed at elucidating AF4 protein cross-talk.
Despite extensive preclinical studies aimed at therapeutically targeting the TGFβ signaling pathway, there is a lack of reports in which TGFβ inhibitors are combined with paclitaxel.
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