Sentence examples for extensive stimulation of from inspiring English sources

However, extensive stimulation of ROS generation in mitochondria has been shown to be able to induce cancer cell death, and is one of the major mechanisms of action of many anticancer agents.

This route of ATP generation is most important for refilling the PCr energy store in oxidative tissues, e.g. upon extensive stimulation of muscle contraction and thus is relevant for recovery after exhausting exercise (Quistorff et al. 1993).

During sepsis, in addition to extensive stimulation of the innate immune system and phenotypic modification of the endothelium, white blood cell activation and complement system activation leads to the release of a number of mediators or cytokines (Jean-Baptiste 2007).

In brief, breaking tolerance to enable these cells to access the islets requires a remarkably extensive stimulation protocol, mimicking some of the effects of acute viral infection by repeated stimulation, immunization and TLR ligation (Figure 2A).

However, the hormone did not alter the extensive stimulation by IL-1β of IL-6 synthesis (Table 2).

A more extensive recent analysis of this model showed an average 10-fold stimulation of RV D3 activity in the CHF group, amounting to ~20% of the level of D3 activity found in brains of these rats [ 31].

Although extensive research has been done on short-term microbial responses to GBHs (see "Stimulation of phytopathogenic microorganisms"), only a small number of studies have sought to observe longer-term (multi-year) effects [37, 57 59].

Despite extensive investigations, no tissue pathology, structural abnormalities, or evidence for a source of chronic stimulation of pain afferents have been detected in fibromyalgic patients [ 54].

Furthermore, the two-cough response occurred most frequently on stimulation of the posterior, basal parts of the lung, where fibrosis is most extensive.

To establish the functions of different carp chemokines during inflammation, we performed an extensive analysis of expression profiles of carp CXCL8_L2, CXCa_L1, CXCb and the receptors CXCR1 and CXCR2 after in vitro stimulation of leukocyte subpopulations.

Indeed, several lines of evidence suggest that extensive inflammatory stimulation may induce EPC dysfunction in humans.