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Proteomic analysis indicated extensive shedding from extra-cellular domains of proteins expressed on the cell surface, and remarkably high secretion rates for some proteins (nanograms per million cells per hour).
These cells showed extensive shedding of extracellular matrix and appeared bare.
Cells harbouring hcl1pVV16 showed an extensive shedding of extracellular matrix from the surface (Fig. 6B and 6D).
Detailed exploration of the data revealed several interesting biological phenomena, including extensive shedding of extra-cellular domains for proteins expressed on the cell surface and high secretion rates of a subset of proteins.
Additionally, the more extensive shedding of Mah might cause pig-to-pig transmission and contribute to the higher incidence of infection caused by this subspecies.
When extensive shedding was obtained over the 16 h treatment period, this was reflected in reduced adherent cell yields (data not shown).
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The cash cushion provided by the sale of these securities allowed Lucent to continue functioning relatively normally even as it went through an extensive restructuring process, shedding units and halting output of some products.
This disease involves extensive mycobacterial shedding, which accounts for the high contagiousness, and ends with fatal enteritis.
Here, we exploit extensive data on pathogen shedding densities and the distribution of cases, collected from the same population within the same spatio-temporal window, to expose the comparative epidemiology of independent Escherichia coli O157 strains.
Our data also indicates extensive cell surface protein shedding in tumor cells obtained from ascites.
Careful comparisons, particularly based on more extensive phylogenies, will shed light on overlooked evolutionary implications.
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