Your English writing platform
Discover LudwigExact(5)
Extensive resonance doubling arises from a cis– trans peptide transition at Gly, whereas linebroadening appears due to a concerted shift in the neighbouring torsion angles.
The H-N-HSQC spectrum shows that most of the H frequencies of the backbone amides are clustered within a ∼1 ppm area with extensive resonance overlap.
Substitution of valine at residue 87 inhibits this ~100 μs transition to the minor form which, in turn, precludes the larger scale transition responsible for the extensive resonance doubling.
Having established that the extensive resonance doubling of FKBP12 arises from the slow cis– trans isomerization of the peptide linkage between Pro and Gly, we then examined the structural basis for the much more rapid linebroadening conformational dynamics of the 80′s loop.
The simplest mechanistic interpretation consistent with these data is that the two slowly interchanging Gly peptide configuration states, monitored by the extensive resonance doubling, interchange with each other only via a more weakly populated transient state in which the ϕ torsion angle of Gly is negative, whereas the peptide configuration remains trans.
Similar(55)
That can have wide resonance.
By 1996, on the basis of extensive magnetic resonance imaging (MRI) and histological examination in both humans and laboratory animals, it became apparent that the original autism lesion occurs just before or shortly after neural tube closure.
However, for heparin-derived oligosaccharides larger than tetrasaccharides, there can be extensive overlap of resonances for the H protons.
The N HSQC and C HSQC spectra of the hE THF NADP+ and hE:FOL NADP+ complexes are virtually indistinguishable, whereas the spectrum of the hE THF NADPH complex shows extensive broadening for resonances of residues near the active site.
Spectral assignments can be challenging, and Turner et al. [21] have published extensive lists of P resonance peaks that provide a guideline for the identification of both Pi and Po.
We introduce a simple and general XML format for spin system description that is the result of extensive consultations within Magnetic Resonance community and unifies under one roof all major existing spin interaction specification conventions.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com