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In conjunction with extensive refinement of the trap and electronics design of the Orbitrap analyzer, this method allows completion of the excitation process and initiation of detection within a fraction of a millisecond after ejection of ions from an external storage device into the Orbitrap analyzer, thus avoiding baseline roll and large non-linear phase corrections.
We would argue that a centuries-long record of failures to prevent or limit war despite ongoing evolution and extensive refinement of the just war framework should impel the Church toward a new moral framework.
Therefore, as part of the peripheral site, loop 2 of AgAChE requires extensive refinement.
Analysis of these ESTs provides direct evidence that over 40% of the ab initio predicted genes are indeed transcribed into mRNA and has allowed extensive refinement of the gene models, as described below.
The identification of the methylotrophic and non-methylotrophic reactions was based on both theoretical and experimental considerations, including i) physiological parameters ii) genetic and biochemical data, iii) omics data (transcriptomic, proteomic, metabolomics), and extensive refinement.
Candidate reactions suggested by GapFill were chosen from the BiGG database; this database contains genome-scale models that have undergone extensive refinement and validation, and thus is a resource of high-confidence reactions [ 32].
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Investment in the development of user-friendly outbreak reporting tools for local health departments might therefore provide better information on outbreaks than extensive refinements of AODAs.
In order to build a genome-scale metabolic model of S. platensis C1, the genome-scale metabolic network was reconstructed according to a series of extensive refinements (Fig. 1 and see also Materials and Methods).
Upon annealing, martensite reverts to austenite leading to extensive grain refinement.
Extensive grain refinement under ECAP was provided by a dispersion of Al6Mn particles with an average size of ∼25 nm that precipitated during the homogenization annealing at an intermediate temperature.
The large sample size enabled extensive model refinement and subgroup analyses in three ways.
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