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Extensive recent work demonstrates that α2M* is a more potent regulator of glucose and lipid metabolism than insulin in cancer cells, but not normal cells (12).
Though there has been extensive recent work on the estimation of FDRs at the peptide-level (Choi and Nesvizhskii, 2008; Kall et al., 2008), there is no consensus at the protein identification level (Tabb, 2008).
We originally called this variant PIPkin IγC, but here, to introduce consistency in nomenclature with more extensive recent work on PIPkin Iγs (see above), we refer to PIPkin IγC as Iγ93.
In an extensive recent work by Orr et al. [ 57], changes associated with activation and cell cycle initiation were investigated both on a systemic level as well as in terms of proteins specifically recruited to chromatin or to the nuclear lamina.
In this review, we have introduced the basic concept of the Wnt signaling pathway, summarized the current studies on the role of the Wnt signaling pathway in metabolic homeostasis and the development of metabolic diseases, presented current disputes on the function of Wnt signaling in pancreatic islet β-cells, and discussed the extensive recent work on TCF7L2 as a diabetes susceptibility gene.
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Because this research has received extensive treatment in recent work on free will, we will not consider it further, but instead refer interested readers to the sources cited above and to Mele 2011 for critical discussion and references.
We refer interested readers to the introduction and reference list of [4] for a concise and extensive overview of recent works.
Many different epigenetic pathways act in mammalian cells and recent work has highlighted extensive interactions between them 1.
The human salivary amylase genes display extensive copy number variation (CNV), and recent work has implicated this variation in adaptation to starch-rich diets, and in association with body mass index.
In a recent work [1], we used extensive atomistic molecular dynamics simulations with explicit solvent to study the binding of an SH3 domain with its binding partner as a general example for protein binding mediated by modular protein domains.
Recent work has revealed an extensive family of Fe(II) and 2-oxoglutarate (2OG) dependent oxygenases encoded in the human genome (reviewed in [1]).
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