Sentence examples for extensive pathways that from inspiring English sources

These extensive pathways that limit heterochromatin assembly might be a response to the high enzymatic activity of Clr4, which is likely required for heterochromatin assembly in an otherwise highly compact and active genome.

Experimental studies on the biological mechanisms of prostate cancer have revealed extensive signaling pathways that provide communication between cancer epithelial cells, stromal cells, and the ECM within tumor microenvironments.

We observed transcriptional changes consistent with these processes and the extensive intercellular signaling pathways that may regulate morphogenetic events during metamorphosis.

In contrast to our increasingly extensive knowledge of pathways that regulate stem cell properties in the lung during development and regeneration, not much is known about the molecular mechanisms that keep lung stem cells largely quiescent during homeostasis or in check after a regenerative response to prevent tissue overcrowding and dysplasia.

Despite extensive knowledge about the regulatory pathways that control σE activity, the stresses that activate these pathways, and the genes that σE transcribes, the essential role of σE in the cell has remained elusive.

Together, these studies demonstrate extensive interaction between the signaling pathways that regulate stem cell self-renewal.

With the detailed characterization of these genes, it is becoming increasingly clear that many of them function either in common signaling pathways or in overlapping molecular pathways that have extensive cross-talk.

In contrast, a recent study on four cestodes identified extensive losses of genes and pathways that are broadly conserved in other animals as well as the origin of specialized metabolic pathways adapted to extract nutrients from the host [ 91].

Understanding the cellular response to Hsp90-targeted therapeutics is complex and multifaceted, given the extensive list of client proteins and pathways that are regulated by this protein.

In addition to manipulating host factors that promote viral replication, influenza virus influences host signaling pathways that lead to extensive cell death and tissue damage during late stages of infection.

The results indicate that there may be extensive crosstalk between MAPK signaling and signaling pathways that are regulated by cellular levels of PIs or IPs.