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The full strength of microarray interpretation lies in the possibility of extracting information beyond the single gene level to address questions on the co-regulation of genes, on the identification of gene networks and entire extensive pathways of genes acting in the same physiological process.
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Our analysis shows, however, that the establishment of extensive pathways for Chinese hospitals has not led to highly compliant care.
We next complemented analysis of the siRNA screens with extensive pathway analyses of the relevant literature, using MetaCore (GeneGo; Thomson Reuters), Ingenuity Pathway Analysis (IPA; Ingenuity Systems), Pathway Studio (Elsevier/Ariadne Genomics) and our own extensive curation.
The Biological Process domain of the Gene Ontology database provided the most extensive pathway assignment.
A greater number of sections were available than for patient 1, permitting more extensive pathway evaluation (Figure 5).
We propose that organism-specific differences in the behaviour of SAC are likely to reflect evolutionary divergence in the mechanics of spindle assembly rather than extensive differences in the pathways of checkpoint signalling.
The genome-scale model presented here includes the extensive fatty acid metabolism pathways of M. tb, in addition to rest of the metabolic network.
The investigation of these outbreaks may allow identification of the pathways of the extensive human infection that comes from the cattle Campylobacter reservoir and support control measures against this large burden of disease.
In the current study, we aim at an extensive unbiased search of tentative dissociation pathways of ligands from LFABP.
Although public metabolic collections includes an extensive set of pathways from all species (37, 39), there is a limited notion of variants of the same pathway, corresponding to alternate routes which can transform the same set of compounds (i.e. 'variants' allows one to take into account metabolic variation between species).
The lack of an extensive definition of pathways focusing on the current query genes makes it hard to accurately evaluate parameter estimations.
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