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Whilst tissue microarrays are available from commercial sources, many pathology laboratories prefer to make in-house arrays from their often extensive pathology archive to facilitate the correlation of their findings with clinical parameters.
One of the characteristic findings in SEB-induced TSS is extensive pathology to the small intestines, which is associated with changes in the gut permeability to macromolecules.
Extensive pathology studies of mice vaccinated with Listeriaat showed no deleterious side effects.
Because of the more extensive pathology examination of sentinel lymph nodes (SLNs), small metastases are observed more frequently.
These only show UPR activation in aged mice, despite extensive pathology much earlier in younger mice [ 50].
Any future clinical use of CpG ODN for AD would likely target a population of whom a substantial proportion will already have extensive pathology.
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An apparent subadult male Allosaurus fragilis was reported to have extensive pathologies, with a total of fourteen separate injuries.
Indeed, it is possible that the more extensive pathologies observed by SEM are representative of ischemic stroke, but take on this appearance during the vascular corrosion casting process.
Such distal effects challenge more traditional views of neuropathology as they reveal how extensive covert pathology might accompany localised overt pathology, and so impair memory.
The purpose of the present study was to determine whether the ε4 allele of APOE is associated with more extensive brain pathology in MS using structural and diffusion tensor MRI.
We have identified extensive inclusion pathology with a very similar distribution in two quite different mouse models of HD.
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