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Extensive panels of relapsed human tumour cell lines are required to reflect the heterogeneity of clinical resistant disease.
At the transcriptome level, microarray analysis and RNA-Seq have been used to document global mRNA expression across extensive panels of human cells and tissues (Ramaswamy et al., 2001; Su et al., 2002), and to examine features of RNA regulation, such as alternative splicing (Braunschweig et al., 2013).
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The analysis uses an extensive panel data that allows an analysis of within person variation over time.
The life course calendar can be advantageous, especially if it is employed to supplement extensive panel studies.
A full systemic workup was undertaken, and patients underwent an extensive panel of investigations, with the aim of excluding other causes.
We assembled an extensive panel data set from the United States including rates of suicide, antidepressant prescriptions, firearm ownership, and other covariates of interest.
In the present studies, we examined the transcriptomic response to PTH in an osteocyte cell model and found that this hormone regulated an extensive panel of genes.
Here we investigated the effects of 10 phenothiazine compounds on NOX activity using an extensive panel of assays to measure production of ROS (Amplex red, WST-1, MCLA) and oxygen consumption.
An alternative top-down approach was developed to define composition in Vibrio cholerae biofilms and relied on an extensive panel of NMR measurements to tease out specific carbon pools from a single sample of the intact extracellular matrix.
This is the first study to describe the epigenetic state of abnormal human sperm using an extensive panel of DNA methylation assays.
This is also the first study to include an extensive panel of TSGs (19 in our study), whereas most of the previous studies focused only on a single gene or a small panel of genes.
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