Likewise, genes that are important for AIEC survival and extensive intracellular multiplication have been identified by use of cultured murine macrophages.
This combination of ecological, physiological and genetic conditions including extensive clonal multiplication, natural release of DNA, competence development, DNA uptake and genome integration, demonstrates the interest in R. solanacearum as a model for studying HGT regulation.
During disease evolution there is extensive parasite multiplication attaining a high parasite burden in the spleen and liver.
On the other end, lepromatous leprosy (LL) is a progressive and disseminated disease characterized by extensive bacterial multiplication within host cells (Scollard et al., 2006).
During the course of VL infection there is extensive parasite multiplication that results in a high parasite burden in the spleen and liver.
At the other, lepromatous leprosy (LL) is a progressively disseminating disease characterized by extensive bacterial multiplication within host cells and low cell-mediated immunity (CMI) to the pathogen.
The life cycle of malaria parasites consists of an alternation between periods of rapid multiplication requiring extensive DNA replication and periods of cellular differentiation, each phase requiring transcription of different sets of stage-specific genes (for review see Kooij et al., 2006).
Chromosome counts suggest that between 30 and 80% of angiosperm species are polyploid, while genomic studies of selected model and crop species reveal evidence of extensive ancient genome-wide multiplications.
Ki-67 is a tumor associated antigen that has tremendous multiplication capacity and extensive influence on cell proliferation.
