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Instead, an extensive mass of coiled sperm bundles accumulates at the base of Ntl mutant testes (Fig. 4 B, D, F, H asterisks). Presumably because of the great physical complexity of the sperm individualization process [53], [54], a large proportion of male-sterile mutations produce elongated cysts that fail to be matured into individual sperm.
Infection severity for C. hepaticum was graded according to the extent of fibrotic burrows in the liver (0: absent; 1: few fibrotic burrows in one hepatic lobe; 2: few fibrotic burrows in more than one lobe, or an extensive mass of fibrotic burrows in one lobe; 3: extensive masses of fibrotic burrows in more than one lobe).
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For an extensive mass spectrometric interrogation of the platelet proteome, the gel lane containing the sample was cut into 12 14 equally sized sections irrespective of staining intensity and in-gel digestion of the bands was performed according to published protocols [34], [65].
Therefore, we conducted an extensive mass spectrometry analysis of cellular sphingolipids in KCN-treated HeLa, 143BΔCOX and COX10−/− cells to monitor the possible modifications of cellular sphingolipid contents upon COX dysfunction.
We provide data on gba1 −/− mRNA stability, reduced GCase enzymatic activity and other biochemical readouts including extensive mass spectrometry-based analysis of sphingolipids which all support the presence of a marked biological effect caused by the TALEN-induced 23 bp deletion in gba1 on GCase function.
Its structure (but not its stereochemistry) is determined on the basis of extensive mass spectrometric and NMR analysis.
Extensive mass spectrometric analysis confirmed the presence of three disulfide bonded Cys94-Cys584, Cys2-Cys479 and Cys428-Cys614 and one free cysteine at position Cys406.
By the 1970s, the primary dog RV variant had been eliminated by extensive mass vaccination programs and effective control of stray animal populations (1, 15 ).
Untargeted UPLC-FTMS profiling was expected to generate extensive mass lists corresponding to a wide variety of metabolites, including alkaloids.
c 3-chamber cine SSFP image shows extensive mass-like appearance of a focal hypertrophic cardiomyopathy involving the mid-ventricular septum (arrow).
We performed extensive mass-spectrometric proteomic analysis of CSF OCBs from 5 MS patients; previously described IgG heavy chain variable region (IgG-VH) sequence data sets obtained by deep-immune repertoire sequencing of PB and CSF were used for reference to match proteomic data with IgG-VH transcripts.
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