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When the Fens were extensive, malaria was a problem throughout eastern England, with disease-carrying mosquitos breeding in the marshes.
The study area in Rondônia was the site of extensive malaria epidemic outbreaks in the 19th and 20th centuries related to environmental impacts, with large immigration flows.
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Although there are relatively little data on the duration of immunity, this is consistent with one study from Madagascar that reported reduced rates of fever in infected individuals born prior to the extensive successful malaria control program initiated in the 1950's, suggesting long-term immunological memory [21].
The UK has extensive links with malaria endemic countries and has one of the highest rates of imported malaria in the developed world.
The arrival of thousands of newcomers in the near future, recruited by the Hydroelectric enterprise, to the riverside areas and the vicinity of Federal Highway BR 364, attracted by secondary jobs underscores the potential for extensive spread of malaria infections.
Unfortunately, no extensive survey of malaria in wild macaques in Chantaburi Province was performed during the study.
These findings represent one of the most extensive reports on malaria among refugees in post-emergency sites.
The expert microscopists had extensive experience in malaria microscopy and passed a proficiency test on parasite detection.
Despite extensive investigation, P. malariae was the only pathogen identified.
Extensive introgression in a malaria vector species complex revealed by phylogenomics.
Inhibitors of the plasmepsin family of aspartyl proteases are already established as potential agents against blood stage malaria through extensive data generated in cell culture and mouse models [9] [11].
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