Sentence examples for extensive internalization from inspiring English sources

BFL1ΔC produced extensive internalization of FD-4, but not APC-104, indicating BFL1ΔC forms pores of relatively small size in 100%CL GUV (Figs. 4c, d).

The protein complex could act to anchor the D2 in specific synaptic locations insuring that signaling is rapid and repeatable, and also prevent extensive internalization and recycling of the receptor.

The extensive internalization of C-cadherin observed by Ogata et al. [2] might be a secondary event due to a more severe or prolonged loss of cadherin mediated adhesion caused by prolonged and higher activin or FLRT3 expression, since disengaged cadherin molecules are known to be more susceptible to endocytosis [6] [8].

The results showed extensive internalization of fluorescently labeled Cy3-LOR-2501 (red, Figure 4(b)) and trafficking to the cytosol.

Third, extensive internalization of Na/K pumps also occurs in response to metabolic stress in several other cell types (Mandel et al., 1994; Bortner et al., 2001; Brown et al., 2001; Mann et al., 2001).

Pralatrexate is an antifolate with high affinity for the reduced folate carrier 1 (RFC-1) protein and folylpolyglutamate synthetase (FPGS), resulting in extensive internalization and accumulation within tumour cells.

Following internalization, extensive alterations of bacterial gene expression were observed.

Further, our study suggests that extensive palmitoylation promotes internalization of membrane as a form of 'lipid raft'-dependent endocytosis (Doherty and McMahon, 2009).

Indeed, the low cell surface expression of hGnRHR has precluded extensive study of their internalization or downregulation, and extrapolation from early work with rodent models is difficult in light of the finding that their localization (and therefore their trafficking) differs markedly from that of hGnRHR (9, 42).

Furthermore, after ligand stimulation, the GNNK− isoform displayed more rapid and extensive tyrosine autophosphorylation and faster internalization (Caruana et al, 1999).

TAT47 57 has been shown to direct the internalization of an extensive list of cargoes ranging from small peptides [ 4] to proteins and polymers [ 3, 10- 12], liposomes [ 13, 14], phage vectors [ 15], plasmid DNAs [ 16, 17] and even nanoparticles [ 18].