Sentence examples for extensive interactions that from inspiring English sources
Monomers stacked on top of each other (A and F; Fig. 3b) have extensive interactions that are significantly enhanced by a 'swapping' of N-terminal residues.
DOI: http://dx.doi.org/10.7554/eLife.00828.008 The HECT domain∼Ub architecture is established by extensive interactions that bury ∼2800 Å of surface area between the N- and C-lobes, and Ub.
In line with the features of intracellular IDPs, extracellular structural disorder is heavily post-translationally modified and involved in extensive interactions that organize large molecular assembles while binding multiple interaction partners.
However, due to the extensive interactions that PGC-1 has with multiple aspects of metabolism [ 12], the possibility persists that endogenous dPGC-1 interactions, other than its role as a regulator of mitochondrial activity, play a role in the cellular and/or organismal phenotypes that we observed.
In fact, the toolbelt model according to which PCNA interactors are loosely tethered to the clamp rather than engaging in extensive interactions predicts that an unstructured peptide harbouring the relevant interaction motifs would probably be most suited as flexible tether.
Instead, the results indicate extensive folded interactions that span the full length of the molecule and include surface accessible and protease sensitive loops that do not mark domain boundaries.
Therefore, the Hsp90 binding TPR motifs on the N-terminus of the trypsin cleaved Unc45bFlag remain associated with the C-terminal UCS domain, suggesting extensive folded interactions that span the full length of the molecule.
The polyhedrally interdigitated outer lattice is emblematic of the extensive protein protein interactions that underpin the formation of a clathrin-coated vesicle.
The interface between two Flp monomers that partake in the trans donation of tyrosine and assembly of a functional active site displays extensive protein-protein interactions that bury a large surface area of ∼1500 Å2 [31].
Effective application of systems biology to emerging model species including avians requires extensive interaction data that are often unavailable.
For example, we have recently undertaken exhaustive curation of the extensive interaction networks that control the state of chromatin modification and protein ubiquitination in both yeast and humans [ 4].
